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A. MUSE (available since 1997) employs a small, specially-designed plastic plunger that is placed on the tip of the penis. Once the plunger is pressed, a rice-size pellet of medication (alprostadil) is pushed into the urethra. Moisture left by urine causes the pellet to dissolve, triggering an erection minutes later. Certainly less invasive than a hypodermic injection of medication, MUSE, an acronym for "medicated urethral system for erection," turns out to be a poor solution. Many men complain of a burning pain in the penis after the drug has been inserted, and there is a small risk of urethral injury. Since the efficacy of MUSE is extremely low - 10 percent or less, according to on 1998 study and the side effects are worse than injection therapy, I don't recommend it as a first-line treatment after a radical prostatectomy.
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